Rutin

DB01698ApprovedInvestigationalSmall molecule

Rutin is a flavonoid found in over-the-counter vitamin supplements. A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc.

Mechanism: Pharmacologically active on Aldo-keto reductase family 1 member C3
Curator reviewed
Formula / weight: C₂₇H₃₀O₁₆ · 610.5175 g/mol (avg)
First approval: Canada, 1967
Also known as: Phytomelin · Rutoside · Sophorin · Vitamin P
Code names: C.I. 75730 · NSC-9220

Resolves to

Compound

UNII5G06TVY3R7CAS153-18-4ChEMBLCHEMBL226335ChEBI28527PubChem5280805KEGGC05625

Clinical / RWD

RxNorm9500ATCC05CA01ATCC05CA51PharmGKBPA451291

Structure

InChIKeyIKGXIBQEEMLURG-NVPNHPEKSA-NSMILES

C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC3=C(OC4=CC(O)=CC(O)=C4C3=O)C3=CC(O)=C(O)C=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

Targets

P42330AKR1C3P16152CBR1

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

37Drug interactionsStructured to mechanism, not free text

15Clinical trialsPhase, status and sponsor resolved per trial

5Structured indicationsCondition, population, route and combination as fields, not prose

19Marketed productsAcross 5 countries and 14 labellers

2ATC codesIncluding every combination product, plus 15 drug categories

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Rutin, and which of those have an active Phase 3 trial?

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